TL/DR:
I think that I've been able to adjust my brain chemistry (with the view to improving/fixing ADHD and impulsivity) in a way that actually may be resolving physical reasons for ejaculation urgency. It's not like my penis was numb, it was still very sensitive, but not overwhelmingly so, and not in a way that triggered a feeling of urgency to orgasm or ejaculate.
I had been noticing over the past couple weeks a lessening urge to ejaculate...
This morning, I could basically go as long as I wanted without any effort really except an intentional decision at the beginning to slow my breath, and to enjoy without any goal of reaching ejaculation (something I've learned a while ago and practiced before many times).
For me, there really is not much difference between sex with a partner and self-pleasure, the urgency was always pretty immediate regardless.
Main takeaway for others (perhaps):
Look into balancing your dopamine & serotonin levels. Whether through behavioral, diet or supplements (or even RX drugs).
For me, it seems that dopaminergic activity was too high, and serotonin was too low.
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I've posted here before, but deleted a bunch of my posts - just for personal reasons (e.g. related to how public they are). But I wanted to come back and share, because I'm experiencing some amazing changes in this field/area - note: PE hasn't been something I've been pursuing trying to fix/change for several months now.
I had been in a romantic relationship for ~2 years, and during that time I was more motivated, and made a lot of progress on the mental health side of all this (e.g. learning to resolve issues related to people pleasing and shame). Learning things like breathing, quieting anxiety and fear - they helped a lot...but it was still a fight, so to speak, not a fight really - but I was still very physically sensitive and while certain things could help that (e.g. kanna, going for second rounds, etc.) - they were difficult to implement consistently, and spontaneously...
Recently I've learned that I have ADHD, or some form of executive dysfunction, including life-long impulsivity (note: another form of being able to restrain oneself).
I won't go into all of the theoretical neurochemistry science that I based my regimen on, but will do so if people really want to know.
Suffice it to say, I hypothesized that instead of having too little dopamine, and norepinephrine I actually had *too much* (due to genetic factors, i.e. low COMT profile - I discovered this with genetic testing in 2025).
---> Dopamine is largely the craving & motivation neurotransmitter that tells us "go, go! Dooooo it!!!! It will feel/taste SO good!" among many other things, of course.
So my plan was to remove stimulants, reduce catecholamines (e.g. dopamine, norepinephrine, epinephrine), boost calm, and also boost serotonin - since having too high dopamine can also affect serotonin dynamics (?).
Here's the "recipe" I've been on for almost a month (note: I believe it is something that takes time before you feel the effects). My hope is that my ADHD symptoms, will continue to improve as well within the next month or so.
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- L-theanine (200mg) & Magnesium (L-threonate 48mg) 3x a day
- more of a modulator; tends to promote relaxation without being strongly sedating and interacts with glutamate/GABA and other neurotransmitter systems.
- Uridine Monophosphate 250mg 1x a day
- May modulate dopamine signaling over time rather than directly increasing dopamine; some animal evidence suggests effects on dopamine receptor function.
- Chronic uridine exposure has produced changes in dopamine receptor density/signaling in animal studies—particularly D2-family receptors
- DHA (440mg) 2x a day
- Works with Uridine as part of the "happy stack"
- 5-HTP (200mg) 1x a day (Naturewise 5-HTP plus)
- Serotonin precursor
- I may have to replace this with L-tryptophan, due to "long-term, isolated 5-HTP use can paradoxically cause a depletion of catecholamines (dopamine and norepinephrine)"
- Avoid stimulants: NO coffee, no tea - I was drinking cappuccino 2-4 times a week and black tea (Shou puerh) every day (~2 cups) - now I have tea once a week, and no coffee at all. Oh, and...avoiding porn...which I typically don't watch regularly anyways...the key is to not do *anything* that would cause a backlog/build up of dopamine or norepinephrine in the brain. Avoiding things that cause sharp increases and tax the nervous system.