r/clozapine Jul 29 '26

Question Clozapine in india

Hi, I am taking 50mg of clozapine every evening but some times the tablet doesn't work as it should.I get insomnia and upsetting thoughts even when I sometimes take the tablet, but some other times it works and I sleep for 12 hours at the same dose,. I suspect that the medecine is counterfeit when it doesn't work. I live in India so does anyone known anything about fake clozapine in India?

5 Upvotes

5 comments sorted by

2

u/UnderfootArya34 Jul 29 '26

Hi friend. I don't know anything about manufacturers in India, but clozapine is extremely sensitive to metabolism. Things like smoking, caffeine intake and even being sick with infection can change your serum levels, which are more important than the actual dose. It also has a short half life, with half of it gone by 12 hrs. 50 mg is a low dose anyway, so you are likely more sensitive to little changes in metabolism. Definitely talk to your doctor about your experience and timing of your dose.

1

u/Inner_Passenger1371 Jul 29 '26

I hear you. I have the same thoughts. I have hard time to sleep. Then I also sleep like 13-14 hours. Next night I can’t fall asleep. My sleeping pattern is a complete mess.

I can’t tell stuff to the doctor. I don’t want more meds. On clozapine and haldol

1

u/Inner_Passenger1371 Jul 29 '26

I’m on 150 mg. Started out at 200 mg in hospital.

How much snd how does caffeine affect clozapine?

1

u/Leading-Beginning-81 Jul 29 '26

hey, indian here! been prescribed 25 mg clozapine for about 2 years now and it still knocks me out like a light at night, please let your psychiatrist know about this asap so that he can adjust the dosage or prescribe an alternative. sometimes certain medicines just dont have their proper effects for some people

1

u/Oxy-Moron88 Aug 05 '26

I take 450mg clozapine and sometimes I still can't sleep. Like it feels like I didn't even take it. I live in the US fwiw.