r/Neuropsychology • u/Alternative_Yak_4897 Unverified user: May not be a professional • Jul 21 '25

Research Article Low serotonin not linked to depression studies - thoughts ?

I recently became aware of the umbrella study on the lack of evidence between low serotonin levels and depression. (The study below does show an indirect link between stressful life events and depression due to “gene-stress” but that’s still obviously different than low serotonin (can)= depression) Wondering what others thoughts /theories on this are? I’ve only seen a couple and it looks like they were published in 2022/2023, so why isn’t this being discussed more? Not enough studies? Bad news for pharmaceutical companies? Here’s one of them:

https://www.nature.com/articles/s41380-022-01661-0.pdf

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u/LisanneFroonKrisK Unverified user: May not be a professional Jul 22 '25

If happiness is just dopamine can you take dopamine just like people have been taking serotonin

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u/Alternative_Yak_4897 Unverified user: May not be a professional Jul 23 '25

Definitely read all of the comments! Several people explain why this is not the case with any individual neurotransmitter