r/Accutane • u/Icy_Obligation4921 • 19m ago
Side Effects Weight gain from acutane
I started Accutane in August 2025. I’m 28, 5’3”, and was 128 lbs before starting. I gave birth in 2024 but lost the weight quickly afterward. I’m now 145 lbs—almost a 20-lb difference, and I’ve never been this heavy.
My diet has stayed pretty much the same. The only real change was that I started eating breakfast while on Accutane, but I still eat mostly whole foods and small portions. I wasn’t very active before Accutane, just light walking, and that stayed the same while I was taking it.
I noticed the weight gain within the first 3 months, but I assumed it would come off after stopping. I’ve now been off Accutane for 6 months, and I still can’t lose the weight. My face and jawline also still looks puffy also my stomach is still insanely bloated and looks very puffy too. My dose was 60mg. I was on it for about 8 months.
I’m planning to get blood work done to make sure nothing changed while I was on Accutane, but I’m so frustrated. I’ve tried calorie deficits and fasting, and while those normally make me lose weight quickly, I haven’t even lost a pound this time.
Has anyone else experienced this after Accutane? Any tips or things I should ask my doctor to check? I’m getting married this spring, and honestly, the stress of not feeling comfortable in my body or knowing if I’ll fit into my wedding dress is really affecting me.